Огляд присвячено ролі біогербіцидів у контролюванні бур’янів, залученні їх як альтернативи синтетичним гербіцидам, в тому числі для подолання резистентності до дії синтетичних гербіцидів. Розглядаються можливості їх сумісного застосування із синтетичними гербіцидами для захисту посівів від бур’янів. Наводиться короткий історичний нарис розвитку біогербіцидних технологій, розглядається сучасне поширення біогербіцидів у світі та проблеми їх застосування. Показано, що біогербіциди мають різноманітне природне походження. Джерелами отримання біогербіцидів можуть бути алелопатичні бактерії і рослини, гриби й мікотоксини, виділені з них. Окрема увага приділяється ефірним оліям, як речовинам з потенційною гербіцидною активністю. Розглядаються фізіологічні особливості впливу специфічних і неспецифічних біогербіцидів на бур’яни, їх селективність щодо окремих їх видів, так і культурних рослин, а також проблеми, пов’язані з цим. Обговорюються особливості пошуку рослинних видів-мішеней для різних типів і форм біогербіцидів. Описуються деякі ідентифіковані сполуки природного походження з гербіцидною активністю та зв’язок між їх хімічною структурою й фітотоксичністю. Розглянуто проблеми, пов’язані з виробництвом, економічною ефективністю застосування біогербіцидів в агропромисловому секторі та можливі шляхи їх вирішення. Окремий розділ присвячено найсучаснішим технологіям розробок нових біогербіцидів і синтетичних гербіцидів за допомогою біотехнологічних методів, а також залучення штучного інтелекту в ці процеси. Аналізуються їх потенційні переваги, пов’язані насамперед з істотним зменшенням строків ідентифікації гербіцидів природного походження, їх скринінгу та, в підсумку, часу розробки нових гербіцидів природного походження.
Ключові слова: бур’яни, резистентність, біогербіциди, синтетичні гербіциди, скринінг, мікогербіциди, алелопатія, бактеріальні гербіциди, ефіроолійні гербіциди
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